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You should call your doctor if you experience: Palpitations lasting more than a few minutes or occurring frequently Chest pain, pressure, or discomfort Dizziness, fainting, or extreme fatigue Shortness of breath Irregular heartbeats that feel very fast or out of control Your doctor may check your heart health through tests such as an electrocardiogram (ECG), a Holter monitor, or blood tests to check electrolytes and thyroid function

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Switching between tirzepatide and semaglutide does not fundamentally change the duration question, both are long-term therapies